Administration of curcumin affects the anxiety behavior in Wistar rats after formaldehyde injected

The curcumin is part of the curcuminoids family. Present in spice turmeric a vegetable alkaloid obtained from Curcuma longa. Many studies have been carried out to describe multiple biological actions curcumin. positive antidepressant and anti-anxiety effects are most likely due its ability normalize specific physiological mechanisms, addition being potent antioxidant anti-inflammatory agent. Curcumin also protects brain simultaneously acts on several mechanisms related depression. It considered be promising therapeutic target for treating depressive behaviors. Through this work, we will prove protective effect anxious behavior Wistar rats complications induced by administration toxic product that formaldehyde. To fact, 25 white strains (250±50 g) were separated into five experimental batches: control batch (T; n = 5), vehicle (CV; (CC; one formaldehyde (FV; 5) (FC; 5). A single intraperitoneal injection diluted distilled water at dose 10 mg/kg. Turmeric dissolved olive oil was administered gastric gavage (60 mg/kg). Our results show benefits against deficits caused reflected disturbance rat degree anxiety using open-field test light dark box test.